Drug Screening and Discovery

Every pharmaceutical researcher has experienced it. That elusive molecule must exist somewhere; it must be able to do what is desired while both inhibiting the desired enzyme and activating the desired receptor. But discovering it is another story. Picking out potential candidates from the enormous pool of available natural and synthetic molecules requires time-consuming and expensive screening for small-molecule medications, which are the backbone of the pharmaceutical business. A vast number of compounds are routinely screened as part of the first step in the drug development process to see whether they have the necessary biochemical or cellular properties. There are always new methods being developed to make this screening quicker, more effective, and less expensive.

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